The Aysén del General Carlos Ibáñez del Campo Region (Spanish: Región de Aysén, pronounced [ajˈsen], or Región de Aysén del General Carlos Ibáñez del Campo), often shortened to Aysén Region or Aisén, is one of Chile's 16 first order administrative divisions. Although the third largest in area, the region is Chile's most sparsely populated region with a population of 102,317 as of 2017. The capital of the region is Coihaique, the region's former namesake.
The landscape is marked by several glaciations that formed many lakes, channels and fjords. The region contains icefields including the Northern Patagonian Ice Field and the Southern Patagonian Ice Field, the world's third largest after those in Antarctica and Greenland. The northern half of the region feature a north-south string of volcanoes. While the western part of the region is densely vegetated and mountainous, the eastern reaches contain open grasslands and much flat and rolling terrain.
Aysén Region was the last major area to be effectively incorporated into the Republic of Chile, with the first permanent settlements emerging in the second half of the 19th century and the inland part being settled at the turn of the century. Until the construction of Route 7 (the Carretera Austral, or Southern Highway) in the 1980s, the only overland routes from north to south through the region were extremely primitive tracks.